I-90 - Don't Even Try It

If you think you're going east for Thanksgiving, go now. We know they're trying to cram some actual work into next week at the office and there's a party you promised you'd attend this weekend, but I-90 is not going to be fully operational by the holiday so throw a bag of cat food on the floor and get in the car ASAP if you don't want to be stuck in Seattle Times's Worst Case Scenario of 30 mile backups.

From WSDOT:

Drivers strongly encouraged to avoid traveling across the Cascades during the Thanksgiving holiday weekend
Thanksgiving weekend lures thousands of extra drivers onto highways. We are making significant efforts to keep traffic moving despite the rockslide lane closures on I-90. However traffic will still overwhelm all of the cross-Cascades routes unless a significant number of drivers choose to cancel their Thanksgiving holiday weekend travel.

Preliminary traffic data indicates that unless many drivers cancel or significantly reschedule Thanksgiving weekend travel, they could spend more than 5 hours sitting in stop-and-go traffic on I-90. Delays on Stevens Pass (U.S. 2) and White Pass (U.S. 12) would also be significant. These travel times will worsen if there's an accident or foul weather.

Seattlest has an alternate suggestion. Instead of canceling plans, why not fire up a Thanksgiving feast at home before you hit the road. Cook a bird, load it into the hatchback and make east. When you come to a dead stop twenty miles before the pass throw a table cloth on the hood and break out the turkey. Then enjoy a roadside Thanksgiving dinner with all of your new friends! You remembered the case of wine, right? Make sure to save plenty of cranberry sauce for whoever breaks out the snowboards first and when you're too full of merlot and tryptophan to hike up for another run say good-bye to your new friends and bust a U back to Seattle. Sorry Aunt Selma, the cell phone wouldn't get a signal up in the pass - See you next year, though.